Real Time Monitoring of Bioprocess and Beyond – A Process Analytical Perspective

Significant attention and interest has been granted towards developing an analytical paradigm with unprecedented capabilities of real time monitoring of the process in the biopharmaceutical development space in the past decade.

The core requirement for real-time analytics involves Process Analytical Technology (PAT), a system for designing, analyzing, and controlling manufacturing through real time monitoring of critical quality and performance attributes to ensure the final product quality. S. Food and Drug Administration endorse the utility of PAT and embrace the integration of novel analytical technologies for process monitoring.